What are OPCs?

OPCs, oligomeric proanthocyanidins, are complex of different plant compounds. They promote strong blood vessels and cardiovascular health. The combination of OPCs and other antioxidants provide a powerful formula that has a host of benefits for the body.

What is Isotonix OPC-3?

The Isotonix OPC-3 marketed by Market America shows antiinflammatory activity and promotes heart health by maintaining normal circulation, blood pressure and cholesterol levels. It also helps maintain normal blood glucose levels. It is made from a combination of grape seed, red wine, pine bark and bilberry extracts. It also contains flavonoids from citrus extract. Because this product is isotonic, it is absorbed quicker into the blood and acts on the body better. Isotonic means “same pressure.” Therefore, this product bears the same chemical resemblance to the body’s blood, plasma and tears. The osmotic pressure of these fluids are the same and thus the nutrients are readily absorbed.

What does the research say?

A lot of research has been done on the therapeutic applications of OPCs. They have found that these compounds have antibacterial, antiviral, anti-carcinogenic, anti-inflammatory, anti-allergic, and help with the dilation and constriction of blood vessels1 . Research also shows that OPC-3 improves cardiovascular risk factors, reduces oxidative stress, improves blood pressure and lowers cholesterol2 . Research also shows that isotonic OPC-3 solution is 6 times more potent than an equivalent tablet form3 .


1. Fine, A.M. Oligomeric Proanthocyanidin Complexes: History, Structure, and Phytopharmaceutical Applications. Altern Med Rev. 2000;5(2):144-151

2. Cesarone, M. R., et all. Improvement in Circulation and in Cardiovascular Risk Factors With a Proprietary Isotonic Bioflavonoid Formula OPC-3. Angiology. 2008;59(4):408-14.

3. Cesarone, M. R., et al. Accelerated Antioxidant Bioavailability of OPC-3 bioflavonoids Administered as Isotonic Solution. Phytotherapy Research. 2009;23(6):775-77.